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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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Laflunimus is an orally active immunosuppressive small molecule that inhibits dihydroorotate dehydrogenase (DHODH) and prostaglandin endoperoxide H synthases (PGHS-1 and PGHS-2). It suppresses immunoglobulin secretion (reported IC50 ≈ 2-2.5 μM) and is used in research probing DHODH-mediated immunomodulation and related biochemical pathways.
High purity: 99.7%.
Molecular formula C15H13F3N2O2; molecular weight 310.27 g/mol.
Targets DHODH and PGHS-1/2, suitable for mechanism-of-action studies.
Appearance: solid, yellow to khaki.
Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years).
Suitable for biochemical and cell-based assays.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Laflunimus (HR325) is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH) used as a research reagent to study immunomodulation and nucleotide biosynthesis. It is supplied as a solid research compound with reported high purity and supporting analytical data for use in biochemical and cellular assays.
Orally active DHODH inhibitor for immunomodulatory studies.
High purity suitable for biochemical and cellular assays.
Available in multiple solid pack sizes, including 50 mg.
Characterized by CAS 147076-36-6 and molecular formula C15H13F3N2O2.
Supplied with supporting analytical documentation, such as RP-HPLC.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More